SAUR36 Antibody

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Description

Functional Roles of SAUR36

SAUR36 is a positive regulator of leaf senescence and mediates auxin-induced developmental processes:

Key Research Findings:

  • Leaf Senescence Promotion:

    • SAUR36 knockout mutants exhibit delayed senescence, retaining chlorophyll and photosystem II activity longer than wild-type plants .

    • Overexpression (without 3′ UTR) triggers premature senescence, marked by elevated ion leakage and senescence-associated gene expression .

  • Auxin Responsiveness:

    • Contains an auxin response element (TGTCTC) in its 5′ UTR .

    • Transcript levels increase 20-fold within 6 hours of auxin (NAA) treatment .

  • Cell Expansion Regulation:

    • saur36 mutants display 67% larger epidermal cells, suggesting SAUR36 inhibits cell expansion .

Potential Applications of SAUR36 Antibody

An antibody targeting SAUR36 would enable precise detection and localization studies. Below are inferred applications based on SAUR family research:

ApplicationMethodologyUtility
Protein LocalizationImmunohistochemistryTrack SAUR36 in senescing vs. young leaves
Expression ProfilingWestern Blot/qPCR correlationValidate transcript-protein dynamics
Interaction StudiesCo-Immunoprecipitation (Co-IP)Identify SAUR36-PP2C.D phosphatase complexes
Mutant Phenotype AnalysisComparative staining in WT vs. saur36Confirm protein absence in knockout lines

Comparative Insights from SAUR Family Studies

SAUR36 shares functional parallels with other SAUR proteins:

SAUR ProteinFunctionMechanism
SAUR63Promotes cell expansionEnhances PM H+-ATPase activity
SAUR19-24Stabilized by N-terminal tagsModulate auxin transport
SAUR76-78Interacts with ethylene receptors Regulates hypocotyl elongation

Research Gaps and Future Directions

  • Antibody Validation: No studies directly report SAUR36 antibody use. Cross-reactivity with other SAURs (e.g., SAUR63) must be tested.

  • Developmental Stage-Specificity: SAUR36’s 3′ UTR-mediated transcript destabilization suggests antibody utility in distinguishing protein levels during senescence .

  • Agricultural Relevance: SAUR36 homologs in crops (e.g., IbSAUR36 in sweet potato) influence root development , highlighting translational potential.

Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
SAUR36 antibody; RAG1 antibody; SAG201 antibody; At2g45210 antibody; Auxin-responsive protein SAUR36 antibody; Protein RESPONSE TO AUXINS AND GIBBERELLINS 1 antibody; Protein SENESCENCE-ASSOCIATED GENE 201 antibody; Protein SMALL AUXIN UP RNA 36 antibody
Target Names
SAUR36
Uniprot No.

Target Background

Function
SAUR36 acts as a positive regulator of leaf senescence and potentially mediates auxin-induced leaf senescence. It plays a role in regulating seed germination by gibberellins and abscisic acid (ABA). Additionally, it contributes to the regulation of light-dependent hypocotyl elongation.
Gene References Into Functions
  1. SAUR36 is involved in the regulation of seed germination by gibberellins and abscisic acid, light-dependent hypocotyl elongation, and apical hook formation or maintenance. PMID: 23503980
  2. Research suggests that SAG201/SAUR36 (AT2G45210) acts as a positive regulator of leaf senescence, potentially mediating auxin-induced leaf senescence. PMID: 23250625
Database Links

KEGG: ath:AT2G45210

STRING: 3702.AT2G45210.1

UniGene: At.43531

Protein Families
ARG7 family
Tissue Specificity
Expressed in embryo, endosperm, growing hypocotyls and shoot apical meristems.

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