scara5 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
scara5 antibody; si:ch211-200p13.4 antibody; Scavenger receptor class A member 5 antibody
Target Names
scara5
Uniprot No.
Target Background
Function
The scara5 antibody targets the ferritin receptor, which mediates the non-transferrin-dependent delivery of iron into cells. It facilitates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface. This process subsequently delivers iron within the cell. The delivery of iron to cells via ferritin is essential for the development of specific cell types, highlighting the existence of cell type-specific mechanisms of iron trafficking during organogenesis. These mechanisms utilize either transferrin or non-transferrin iron delivery pathways.
Database Links
Protein Families
SCARA5 family
Subcellular Location
Cell membrane; Single-pass type II membrane protein.
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