SEMA6D Antibody, FITC conjugated

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In Stock

Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Typically, we can ship your order within 1-3 business days after receiving it. Delivery times may vary depending on your location and the chosen shipping method. For precise delivery timelines, we recommend consulting your local distributor.
Synonyms
SEMA6D antibody; KIAA1479 antibody; Semaphorin-6D antibody
Target Names
SEMA6D
Uniprot No.

Target Background

Function
This antibody exhibits growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. This suggests a potential role as a stop signal for DRG neurons in their target areas, potentially extending to other neuronal types. Furthermore, it may be implicated in the maintenance and remodeling of neuronal connections.
Gene References Into Functions
  1. This study identified, characterized, and functionally analyzed two novel human members of the semaphorin gene family. PMID: 12110693
  2. Semaphorin 6D may play a significant role in the development and progression of gastric carcinoma, with a possible connection to tumor angiogenesis. PMID: 17143962
Database Links

HGNC: 16770

OMIM: 609295

KEGG: hsa:80031

STRING: 9606.ENSP00000324857

UniGene: Hs.511265

Protein Families
Semaphorin family
Subcellular Location
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell membrane; Single-pass type I membrane protein.; [Isoform 4]: Cell membrane; Single-pass type I membrane protein.; [Isoform 5]: Cell membrane; Single-pass type I membrane protein.; [Isoform 7]: Cytoplasm.

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