SH3GLB2 Antibody
Shipped with Ice Packs 
In Stock 
Product Specs
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. Store at -20°C. Avoid freeze/thaw cycles.
Lead Time
Typically, we can ship your order within 1-3 business days after receiving it. Delivery time may vary depending on the purchase method and location. Please consult your local distributor for specific delivery times.
Synonyms
Endophilin B2 antibody; Endophilin-B2 antibody; OTTHUMP00000022320 antibody; PP6569 antibody; PP9455 antibody; Retinoid receptor induced gene 1 antibody; RRIG1 antibody; SH3 containing protein SH3GLB2 antibody; SH3 domain GRB2 like endophilin B2 antibody; SH3 domain-containing GRB2-like protein B2 antibody; SH3GLB2 antibody; SHLB2_HUMAN antibody
Target Names
Uniprot No.
Target Background
Gene References Into Functions
- Research indicates that Endophilin B2, similar to Endophilin B1, plays a crucial role in mitochondrial sequestration and inner mitochondrial membrane (IMM) protein degradation during mitophagy. PMID: 27112121
- Data, including studies in knockout mice, suggest that SH3GLB2 regulates the trafficking of endocytic vesicles and autophagosomes to late endosomes or lysosomes. Despite having an intracellular localization and tissue distribution similar to endophilin B1, endophilin B2 is not essential for mitochondrial apoptosis. PMID: 28455444
- The endophilin B2-plectin complex has potential significance in biological functions related to nuclear migration and positioning. PMID: 23921385
- A nonmutated HLA-A2-binding epitope in the human ortholog SH3GLB2 has been identified. This epitope primed T cells from healthy HLA-A2(+) individuals. PMID: 18303116
Database Links
Protein Families
Endophilin family
Subcellular Location
Cytoplasm.
Tissue Specificity
Detected in skeletal muscle, adipocyte, brain, lung, colon and mammary gland.
Quick Inquiry
Personal Email Detected
Please use an institutional or corporate email address for inquiries. Personal email accounts ( such as Gmail, Yahoo, and Outlook) are not accepted. *
