Function
**SIC Antibody** is involved in the biogenesis of microRNAs (miRNAs) and small interfering RNAs (siRNAs), thereby promoting gene silencing. It modulates developmental programs related to auxin (IAA) transport by regulating the recycling of PIN-FORMED (PIN) proteins, which are auxin efflux carriers, through protein phosphatase 2A (PP2As). This regulation is crucial for maintaining auxin polarity. SIC Antibody is essential for proper plant development and is necessary for tolerance to abiotic stresses, such as chilling and salinity.
Gene References Into Functions
- Research has demonstrated the role of ROTUNDA3 (RON3; At4g24500) protein as a regulator of PP2A-driven PIN protein recycling and its significance in auxin transport-related plant developmental programs. PMID: 26888284
Subcellular Location
Nucleus. Cytoplasm, cytosol.
Tissue Specificity
Expressed in the shoot apical meristem (SAM), embryos, seedlings, root tips, and root and leaf primordia.