SLC35B4 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% ProClin 300. Constituents: 50% Glycerol, 0.01M PBS, pH 7.4.
Form
Liquid
Lead Time
Orders are typically dispatched within 1-3 business days of receipt. Delivery times may vary depending on shipping method and destination. Please contact your local distributor for precise delivery estimates.
Synonyms
SLC35B4 antibody; YEA4 antibody; PSEC0055 antibody; UDP-xylose and UDP-N-acetylglucosamine transporter antibody; Solute carrier family 35 member B4 antibody; YEA4 homolog antibody
Target Names
SLC35B4
Uniprot No.
Target Background
Function
This antibody targets SLC35B4, a sugar transporter responsible for the specific translocation of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from the cytosol into the Golgi apparatus.
Gene References Into Functions
- Glucose levels regulate SLC35B4 expression. This impacts downstream proteins, including Hsp60, potentially by modulating glycosylation patterns within hepatocytes. PMID: 29867058
- Studies have investigated the subcellular localization of SLC35B4. PMID: 21918738
- Reduced SLC35B4 expression has been shown to increase gluconeogenesis in HepG2 cells. PMID: 21507882
- The transport capabilities of SLC35B4 for UDP-Glc and UDP-Xyl have been characterized using Golgi vesicles isolated from transformed cells. PMID: 15911612
Database Links
Protein Families
Nucleotide-sugar transporter family, SLC35B subfamily
Subcellular Location
Golgi apparatus membrane; Multi-pass membrane protein.
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