snx14 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
snx14Sorting nexin-14 antibody
Target Names
snx14
Uniprot No.
Target Background
Function
SNX14 plays a crucial role in maintaining normal neuronal excitability and synaptic transmission. It is believed to be involved in various stages of intracellular trafficking. Notably, SNX14 is essential for autophagosome clearance, potentially by facilitating the fusion of lysosomes with autophagosomes. This protein binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2), a key component of late endosomes/lysosomes, but does not bind phosphatidylinositol 3-phosphate (PtdIns(3P)).
Database Links
STRING: 7955.ENSDARP00000119620
UniGene: Dr.81078
Protein Families
Sorting nexin family
Subcellular Location
Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Cell projection, dendrite.
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