This antibody may regulate transcription elongation by RNA polymerase II. It may also enhance transcriptional pausing at sites proximal to the promoter, which in turn may facilitate the assembly of an elongation-competent RNA polymerase II complex.
Gene References Into Functions
The phosphorylation of SPT5 by CDKD;2 enables it to recruit VIP5 to regulate chromatin and transcription in Arabidopsis. PMID: 28188267
SPT5-like protein emerged in plants as a facultative RNA polymerase elongation factor. [SPT5] PMID: 19343051