sptl-1 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% ProClin 300
Constituents: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
Constituents: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
Form
Liquid
Lead Time
14-16 Weeks (Made-to-Order)
Synonyms
sptl-1 antibody; C23H3.4 antibody; Serine palmitoyltransferase 1 antibody; EC 2.3.1.50 antibody; Long chain base biosynthesis protein 1 antibody; LCB 1 antibody; Serine-palmitoyl-CoA transferase 1 antibody; SPT 1 antibody; SPT1 antibody
Target Names
sptl-1
Uniprot No.
Target Background
Function
SPTL-1 is a component of serine palmitoyltransferase (SPT), a crucial enzyme complex catalyzing the initial and rate-limiting step in sphingolipid biosynthesis. This step involves the condensation of an acyl-CoA species and L-serine. The catalytic core of SPT is a heterodimer; either SPTL1/SPTL2 or SPTL1/SPTL3. SPTL-1 is essential for establishing apicobasal polarity and the proper development of the gut lumen.
Database Links
Protein Families
Class-II pyridoxal-phosphate-dependent aminotransferase family
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