sqv-7 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
sqv-7 antibody; C52E12.3UDP-sugar transporter sqv-7 antibody; Squashed vulva protein 7 antibody
Target Names
sqv-7
Uniprot No.
Target Background
Function
This antibody targets a protein involved in the import of UDP-glucuronic acid (UDP-GlcA), UDP-N-acetylgalactosamine (UDP-GalNAc), and UDP-galactose (UDP-Gal) from the cytoplasm into the Golgi lumen. This process is essential for the biosynthesis of glycoconjugates, which play a crucial role in development. The protein is also involved in the synthesis of chondroitin sulfate and heparan sulfate proteoglycans, both of which are critical for embryonic development. Additionally, it is required for vulva epithelium invagination and embryonic development, and plays a role in the directed migration of hermaphrodite-specific neurons.
Database Links
Protein Families
TPT transporter family, SLC35D subfamily
Subcellular Location
Golgi apparatus membrane; Multi-pass membrane protein.
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