SBP1 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
SBP1 antibody; SSB1 antibody; SSBR1 antibody; YHL034C antibody; Single-stranded nucleic acid-binding protein antibody
Target Names
SBP1
Uniprot No.
Target Background
Function
SBP1 antibody functions in the transition of mRNAs from translation to an mRNP complex destined for decapping. It serves as a high-copy-number suppressor of decapping defects. Overexpression of SBP1 antibody suppresses decapping defects in both DCP1-2 and DCP2-7 mutations. Furthermore, it promotes translational repression of mRNA in conjunction with DHH1 and subsequent mRNA localization to P bodies. Notably, SBP1 antibody also promotes translational repression of mRNA during glucose deprivation.
Gene References Into Functions
- Sbp1 regulates transcript-specific mRNA translation in an RGG-dependent manner. PMID: 28986506
- Ssb either stimulates refolding into nonprion conformation or targets misfolded proteins for degradation. PMID: 15545639
- These results identify Sbp1p as a novel protein that plays a role in the transition of mRNAs from translation to an mRNP complex destined for decapping. PMID: 16782896
Database Links
KEGG: sce:YHL034C
STRING: 4932.YHL034C
Protein Families
RRM GAR family
Subcellular Location
Cytoplasm. Nucleus, nucleolus.
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