GEBPL Antibody

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Description

Absence of "GEBPL Antibody" in Scientific Literature

None of the 10 provided sources mention "GEBPL Antibody." Key antibody databases and repositories, such as the Observed Antibody Space (OAS) , catalog over 1.5 billion antibody sequences but include no entries matching this term. Similarly, clinical-stage antibody therapeutics listed by the Antibody Society show no candidates with this designation.

Potential Terminology Confusion

The term "GEBPL" does not align with established antibody nomenclature:

  • Glycoprotein B (gB) is a well-studied EBV antigen targeted by antibodies like 3A3, 3A5, 8A9, and AMMO5 .

  • Antibody naming conventions typically follow formats like "anti-[target]-[identifier]" (e.g., anti-gB 3A3) or INN/Ig subclass labels (e.g., IgG1) .

Analysis of Similar Antibody Classes

While "GEBPL" remains unidentified, research on glycoprotein B (gB)-targeting antibodies provides insights into analogous antibody development:

Recommendations for Further Investigation

  1. Verify Terminology: Confirm whether "GEBPL" refers to a novel antibody, a typographical error, or a proprietary compound not yet published.

  2. Explore Alternative Databases: Cross-reference with specialized repositories like the OAS interface or structural databases (PDB, SAbDab).

  3. Collaborative Outreach: Contact institutions referenced in the search results (e.g., UCLA , NDM ) for unpublished data or ongoing projects.

Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
GEBPL antibody; At4g25210 antibody; F24A6.50 antibody; GLABROUS1 enhancer-binding protein-like antibody; Mediator-associated protein 1 antibody; Protein GeBPL antibody; Storekeeper-like protein At4g25210 antibody; Transcription factor At4g25210 antibody
Target Names
GEBPL
Uniprot No.

Target Background

Function
GEBPL (GLABROUS1/GL1 enhancer-binding protein-like) is a transcription factor that binds to promoters containing the CryR2 element, 5'-ACATAWCT-3'. Its DNA-binding activity is regulated by interactions with mediator subunits and redox conditions. The oxidized form of GEBPL exhibits a stronger preference for DNA binding.
Gene References Into Functions
  1. Research suggests that the presence of mediator complex subunits MED10a, MED28, and MED32, or changes in redox state, can influence the DNA-binding capacity of GEBPL. PMID: 25877331
Database Links

KEGG: ath:AT4G25210

STRING: 3702.AT4G25210.1

UniGene: At.2577

Protein Families
GeBP family
Subcellular Location
Nucleus.

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