STT3B Antibody
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In Stock 
Product Specs
Buffer
**Preservative:** 0.03% Proclin 300
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
STT3B antibody; At1g34130 antibody; F12G12.5 antibody; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B antibody; Oligosaccharyl transferase subunit STT3B antibody; STT3-B antibody; EC 2.4.99.18 antibody; Protein STAUROSPORIN AND TEMPERATURE SENSITIVE 3-LIKE B antibody
Target Names
Uniprot No.
Target Background
Function
The STT3B antibody targets the catalytic subunit of the oligosaccharyl transferase (OST) complex. This complex plays a crucial role in protein N-glycosylation by catalyzing the initial transfer of a specific glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. This process, known as N-glycosylation, occurs cotranslationally and involves the association of the OST complex with the Sec61 complex at the channel-forming translocon complex, which mediates protein translocation across the endoplasmic reticulum (ER). All subunits of the OST complex are essential for maximal enzyme activity. The STT3B subunit contains the active site, as well as the binding pockets for the acceptor peptide and the donor lipid-linked oligosaccharide (LLO).
Database Links
Protein Families
STT3 family
Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity
Expressed preferentially in the root but also in the shoot.
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