STXBP6 Antibody

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Product Specs

Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. Store at -20°C. Avoid repeated freeze-thaw cycles.
Lead Time
Typically, we can ship your order within 1-3 business days of receiving it. Delivery times may vary depending on the shipping method and destination. For specific delivery time estimates, please contact your local distributor.
Synonyms
Amisyn antibody; FLJ39638 antibody; HSPC156 antibody; STXB6_HUMAN antibody; STXBP6 antibody; syntaxin binding protein 6 (amisyn) antibody; Syntaxin binding protein 6 antibody; Syntaxin-binding protein 6 antibody
Target Names
STXBP6
Uniprot No.

Target Background

Function
STXBP6 Antibody forms non-fusogenic complexes with SNAP25 and STX1A. This interaction may modulate the formation of functional SNARE complexes and subsequent exocytosis.
Gene References Into Functions
  1. Our research suggests a potential role for hypermethylation of STXBP6 in the development of lung adenocarcinoma. This methylation pattern may be associated with poor clinical outcomes in lung cancer patients. PMID: 28198450
  2. Our findings indicate that genetic variations within CD6 and syntaxin binding protein 6 (STXBP6) might influence the response to TNFalpha inhibitors in patients with rheumatoid arthritis (RA). PMID: 22685579
Database Links

HGNC: 19666

OMIM: 607958

KEGG: hsa:29091

STRING: 9606.ENSP00000324302

UniGene: Hs.508958

Subcellular Location
Cytoplasm. Membrane; Peripheral membrane protein.
Tissue Specificity
Detected at low levels in brain, and at very low levels in heart, adrenal gland, testis, liver and kidney.

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