ileS Antibody
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In Stock 
Product Specs
Buffer
**Preservative:** 0.03% Proclin 300
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
ileS antibody; ECIAI39_0027 antibody; Isoleucine--tRNA ligase antibody; EC 6.1.1.5 antibody; Isoleucyl-tRNA synthetase antibody; IleRS antibody
Target Names
ileS
Uniprot No.
Target Background
Function
IleS is an enzyme that catalyzes the attachment of isoleucine to tRNA(Ile). Due to its ability to inadvertently accommodate and process structurally similar amino acids like valine, IleS possesses two distinct tRNA(Ile)-dependent editing activities to prevent such errors. One activity, known as 'pretransfer' editing, involves the hydrolysis of activated Val-AMP. The other activity, designated as 'posttransfer' editing, involves deacylation of mischarged Val-tRNA(Ile).
Database Links
KEGG: ect:ECIAI39_0027
Protein Families
Class-I aminoacyl-tRNA synthetase family, IleS type 1 subfamily
Subcellular Location
Cytoplasm.
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