Function
This antibody targets the TIM22 complex, a key component of mitochondrial protein import machinery. The TIM22 complex facilitates the insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. This process involves the formation of a twin-pore translocase that utilizes the membrane potential as its driving force. Within the TIM22 complex, this antibody's target protein may function as a docking site for the soluble 70 kDa complex, guiding the target proteins through the mitochondrial intermembrane space during transit.