prrB Antibody
Shipped with Ice Packs 
In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 weeks lead time (made-to-order)
Synonyms
prrB antibody; Type-1 restriction enzyme EcoprrI specificity protein antibody; S.EcoprrI antibody; Type I restriction enzyme EcoprrI specificity protein antibody; S protein antibody
Target Names
prrB
Uniprot No.
Target Background
Function
The EcoprrI methyltransferase (MTase) complex comprises M and S subunits, which together methylate two adenine residues within a bipartite DNA recognition sequence on complementary strands. In the presence of the R subunit, the complex exhibits endonuclease activity, binding to the same target sequence but cleaving the DNA at a distance from this site. The enzyme's function (methylation or cleavage) is determined by the methylation status of the target sequence. Unmodified target sites result in DNA cleavage, while hemimethylated sites are modified by the complex's maintenance MTase activity, leading to methylation of both strands. The S subunit dictates the enzyme's DNA sequence specificity; EcoprrI recognizes the sequence 5'-CCAN7ATGC-3'.
Protein Families
Type-I restriction system S methylase family
Quick Inquiry
Personal Email Detected
Please use an institutional or corporate email address for inquiries. Personal email accounts ( such as Gmail, Yahoo, and Outlook) are not accepted. *
