TCEAL3/TCEAL5/TCEAL6 Antibody

Antibody Overview

The TCEAL3/TCEAL5/TCEAL6 Antibody (Catalog ID: C19161) is a polyclonal reagent developed for research applications targeting the Transcription Elongation Factor A (SII)-Like (TCEAL) protein family members. These proteins are implicated in transcriptional regulation, though their specific roles in cellular processes remain under investigation .

Immunohistochemistry (IHC-p)

The antibody is validated for detecting TCEAL3/5/6 in paraffin-embedded tissue sections, enabling studies of protein localization in diseased versus healthy states .

Immunofluorescence (IF)

It is compatible with paraffin-section IF, allowing co-localization studies with other markers in subcellular compartments .

Cross-Species Compatibility

Reactivity spans humans, mice, and rats, supporting translational research across model systems .

Associated Research Areas

The antibody is categorized under Transcription Regulators, aligning with the TCEAL family’s putative role in modulating RNA polymerase II activity. Additional overlapping research areas include:

• Tumor Suppressors/Apoptosis

• Cell Cycle Proteins

• Structural Proteins

Technical Notes

• Conjugation Flexibility: Available in 43 conjugated formats (e.g., Alexa Fluor dyes, HRP) and unconjugated forms for custom assays.

• Companion Assays: Compatible with ELISA kits for quantitative analyses, including colorimetric and chemiluminescent platforms .

Limitations and Considerations

• No peer-reviewed studies directly linking this antibody to mechanistic insights into TCEAL3/5/6 functions were identified in the provided sources.

• Specific epitope recognition details (e.g., linear vs. conformational) are not disclosed in available documentation .