kat-1 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
kat-1 antibody; T02G5.8 antibody; Acetyl-CoA acetyltransferase homolog antibody; mitochondrial antibody; 3-ketoacyl-CoA thiolase antibody; EC 2.3.1.- antibody
Target Names
kat-1
Uniprot No.
Target Background
Function
KAT-1 plays a significant role in ketone body metabolism. It influences the function of lysosome-related organelles (LROs) in a pathway involving serotonin. KAT-1 acts downstream of SIR-2.1 to regulate aging and stress resistance.
Gene References Into Functions
- Research indicates that defects in fatty acid oxidation can shorten lifespan and accelerate aging in C. elegans. Furthermore, KAT-1-mediated fatty acid oxidation is critical for the lifespan-extending effects of overexpressed SIR-2.1. PMID: 20956318
Database Links
Protein Families
Thiolase family
Subcellular Location
Mitochondrion.
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