ddp-1 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
ddp-1 antibody; tim-8 antibody; Y39A3CR.4 antibody; Mitochondrial import inner membrane translocase subunit Tim8 antibody
Target Names
ddp-1
Uniprot No.
Target Background
Function
DDP-1 is a mitochondrial intermembrane chaperone that plays a crucial role in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. It is also essential for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acting as a chaperone-like protein, DDP-1 safeguards hydrophobic precursors from aggregation and guides them through the mitochondrial intermembrane space. The DDP-1/TIM-8-TIM-13 complex facilitates the import of specific proteins, while the predominant TIM-9/TIN-9.1-TIM-10/TIN-10 70 kDa complex governs the import of a significantly larger number of proteins.
Database Links
Protein Families
Small Tim family
Subcellular Location
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
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