TMEM219 Antibody

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In Stock

Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (12-14 weeks)
Synonyms
Insulin-like growth factor-binding protein 3 receptor (IGFBP-3R) (Transmembrane protein 219), TMEM219
Target Names
TMEM219
Uniprot No.

Target Background

Function
TMEM219 Antibody is a cell death receptor specific for IGFBP3. Upon ligand binding, it may mediate caspase-8-dependent apoptosis.
Gene References Into Functions
  1. TMEM219 plays a critical role in Chi3l1-induced IL-13Ralpha2 mediated signaling and tissue responses. PMID: 27629921
Database Links

HGNC: 25201

KEGG: hsa:124446

STRING: 9606.ENSP00000279396

UniGene: Hs.460574

Subcellular Location
Cell membrane; Single-pass membrane protein.
Tissue Specificity
Widely expressed in normal tissues but suppressed in prostate and breast tumor.

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