tank-1 Antibody
Shipped with Ice Packs 
In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
tank-1 antibody; pme-5 antibody; ZK1005.1 antibody; Poly [ADP-ribose] polymerase tankyrase antibody; EC 2.4.2.30 antibody; Poly ADP-ribose metabolism enzyme 5 antibody; Protein poly-ADP-ribosyltransferase tankyrase antibody; EC 2.4.2.- antibody
Target Names
tank-1
Uniprot No.
Target Background
Function
Poly(ADP-ribose) polymerases (PARPs) are enzymes that modify various nuclear proteins through poly(ADP-ribosyl)ation. This post-translational modification is synthesized in response to DNA damage and serves as a critical step in the detection and signaling pathways leading to DNA strand break repair and programmed cell death.
Gene References Into Functions
- PME-5 is a ubiquitous nuclear protein expressed throughout the development of the worm. It is closely associated with chromatin and condensed chromosomes. PMID: 19104912
Database Links
Subcellular Location
Nucleus. Chromosome.
Tissue Specificity
Expressed throughout the head and tail, in germ cells and somatic cells.
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