tni-1 Antibody

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Product Specs

Buffer
Preservative: 0.03% ProClin 300
Composition: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 weeks (Made-to-order)
Synonyms
tni-1 antibody; F42E11.4 antibody; Troponin I 1 antibody; CeTNI-1 antibody; TnI 1 antibody
Target Names
tni-1
Uniprot No.

Target Background

Function

Troponin I is the inhibitory subunit of the troponin complex, a thin filament regulator that confers calcium sensitivity to actomyosin ATPase activity in muscle.

Gene References Into Functions
  1. Troponin I regulates contraction in non-striated actomyosin networks and serves as a crucial cytoskeletal component within the C. elegans reproductive system. PMID: 20388732
  2. It evolved following a gene duplication event originating from the pharyngeal troponin-4 gene. PMID: 15743415
Database Links

KEGG: cel:CELE_F42E11.4

STRING: 6239.F42E11.4

UniGene: Cel.17296

Protein Families
Troponin I family
Tissue Specificity
Strongly expressed in body wall muscle during embryogenesis, reduces during the larval stages to adult. In late-stage larvae and adults, expression is evident in the proximal gonad of both hermaphrodites and males.

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