traY Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
traY antibody; Relaxosome protein TraY antibody; Fragment antibody
Target Names
traY
Uniprot No.
Target Background
Function
Conjugative DNA transfer (CDT) is a unidirectional process involving the transfer of single-stranded DNA (ssDNA) plasmids from a donor to a recipient cell. This mechanism is paramount in the propagation of antibiotic resistance and virulence factors within bacterial populations. TraY, as a component of the relaxosome, plays a crucial role in facilitating a site- and strand-specific cut at the nic site within the origin of transfer (oriT) by the TraI protein. The formation of the relaxosome requires the binding of integration host factor (IHF) and TraY to the oriT region, enabling subsequent TraI binding. Furthermore, TraY positively regulates the expression of tra genes.
Protein Families
TraY family
Subcellular Location
Cytoplasm.
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