tsp-17 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% ProClin 300
Components: 50% Glycerol, 0.01M PBS, pH 7.4
Components: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 Week Lead Time (Made-to-Order)
Synonyms
tsp-17 antibody; C02F12.1 antibody; Tetraspanin-17 antibody
Target Names
tsp-17
Uniprot No.
Target Background
Function
This TSP-17 antibody protects dopaminergic neurons from oxidative stress-induced neurodegeneration. Its mechanism of action may involve the dopamine receptor dop-2, negatively regulating dopamine reuptake transporter dat-1 activity. Additionally, it modulates behaviors associated with dopamine signaling and offers whole-body protection against oxidative stress.
Gene References Into Functions
- TSP-17 exhibits neuroprotective effects and modulates behaviors linked to dopamine signaling. PMID: 25474638
Database Links
UniGene: Cel.23987
Protein Families
Tetraspanin (TM4SF) family
Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Cell projection, axon.
Tissue Specificity
Expressed in dopaminergic neurons, head muscles, vulva and spermatheca.
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