ttll-4 Antibody
Shipped with Ice Packs 
In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
ttll-4 antibody; ZK1128.6 antibody; Tubulin polyglutamylase ttll-4 antibody; EC 6.-.-.- antibody; Tubulin--tyrosine ligase-like protein 4 antibody
Target Names
ttll-4
Uniprot No.
Target Background
Function
TTLL-4 is a monoglutamylase enzyme that modifies tubulin by adding a single glutamate residue to the gamma-carboxyl group of specific glutamate residues on target proteins. It plays a crucial role in the initiation step of the polyglutamylation reaction but is not involved in the elongation step. TTLL-4 preferentially modifies beta-tail tubulin over alpha-tubulin. This enzyme is implicated in the side-chain glutamylation of tubulin within sensory cilia. In conjunction with TTLL-5 and TTLL-11, TTLL-4 is essential for male mating.
Database Links
Protein Families
Tubulin--tyrosine ligase family
Tissue Specificity
Expressed in many sensory neurons in amphid.
Quick Inquiry
Personal Email Detected
Please use an institutional or corporate email address for inquiries. Personal email accounts ( such as Gmail, Yahoo, and Outlook) are not accepted. *
