twk-7 Antibody
Shipped with Ice Packs 
In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
twk-7; twk-8; F22B7.7; TWiK family of potassium channels protein 7
Target Names
twk-7
Uniprot No.
Target Background
Gene References Into Functions
Background Information
- Our research identified TWK-7 as a potential downstream target of the GalphaS-KIN-1/PKA pathway within the gamma-aminobutyric acid (GABA)ergic D-type motor neurons. This epistatic interaction suggests that KIN-1/PKA and TWK-7 might share a common pathway, likely involved in regulating both locomotor activity and locomotion behavior during forward crawling. PMID: 28341653
- Our findings indicate that TWK-7 activity may serve as a mechanism to modulate complex locomotion behavior at the level of specific motor neuron types. PMID: 27535928
Database Links
Protein Families
Two pore domain potassium channel (TC 1.A.1.8) family
Subcellular Location
Membrane; Multi-pass membrane protein.
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