UBE2J1 Antibody
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Product Specs
Buffer
**Preservative:** 0.03% Proclin 300
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
UBE2J1 antibody; NCUBE1 antibody; CGI-76 antibody; HSPC153 antibody; HSPC205 antibody; Ubiquitin-conjugating enzyme E2 J1 antibody; EC 2.3.2.23 antibody; E2 ubiquitin-conjugating enzyme J1 antibody; Non-canonical ubiquitin-conjugating enzyme 1 antibody; NCUBE-1 antibody; Yeast ubiquitin-conjugating enzyme UBC6 homolog E antibody; HsUBC6e antibody
Target Names
Uniprot No.
Target Background
Function
UBE2J1 Antibody catalyzes the covalent attachment of ubiquitin to other proteins. It plays a crucial role in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD).
Gene References Into Functions
- Research indicates that UBE2J1, a member of the UBE2 family, can negatively regulate type I interferon expression, thereby promoting RNA virus infection. PMID: 30157886
- Post-transcriptional regulation of glycoprotein quality control within the endoplasmic reticulum is governed by UBC6e. PMID: 27570074
- Evidence supports a physiological role for HRD1 and UBE2J1 in the homeostatic regulation of MHC class I assembly and expression. PMID: 21245296
- Ubc6e undergoes phosphorylation in response to endoplasmic reticulum stress. PMID: 16720581
Database Links
Protein Families
Ubiquitin-conjugating enzyme family
Subcellular Location
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
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