ubc-13 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% ProClin 300. Constituents: 50% Glycerol, 0.01M PBS, pH 7.4.
Form
Liquid
Lead Time
14-16 week lead time (made-to-order)
Synonyms
ubc-13 antibody; Y54G2A.31 antibody; Ubiquitin-conjugating enzyme E2 13 antibody; EC 2.3.2.23 antibody
Target Names
ubc-13
Uniprot No.
Target Background
Function
UBC-13 is involved in protein ubiquitination, although it lacks intrinsic ubiquitin ligase activity. Heterodimers of UBC-13 and UEV-1 catalyze the formation of non-canonical Lys-63-linked polyubiquitin chains. This activity plays a role in the sorting of Lys-63-linked polyubiquitinated maternal membrane proteins for degradation via targeting to multivesicular bodies. Additionally, UBC-13 may be involved in the ubiquitination and growth of intracellular polyglutamine protein aggregates. A potential role in AMPA-type glutamate receptor trafficking in neurons has also been suggested.
Database Links
Protein Families
Ubiquitin-conjugating enzyme family
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