unc-97 Antibody
Shipped with Ice Packs 
In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
unc-97 antibody; F14D12.2 antibody; LIM domain-containing protein unc-97 antibody; PINCH homolog antibody; Uncoordinated protein 97 antibody
Target Names
unc-97
Uniprot No.
Target Background
Function
UNC-97 is a component of an integrin-containing attachment complex that plays a crucial role in muscle development and maintenance. It is likely involved in adherens junction formation. UNC-97 influences the structural integrity of integrin-containing muscle adherens junctions and contributes to the mechanosensory functions of touch neurons.
Gene References Into Functions
- UNC-97/PINCH is essential for the development of *C. elegans* and is required for the formation of integrin-based adhesion structures. PMID: 17662976
Database Links
Subcellular Location
Cell junction, adherens junction. Nucleus.
Tissue Specificity
Restricted to tissue types that attach to the hypodermis, specifically body wall muscles, vulval muscles, and mechanosensory neurons.
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