vha-10 Antibody

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Description

Terminology Clarification

The term "vha-10" may stem from a misinterpretation or typographical error. Potential related terms include:

  • VHA (Veterans Health Administration): Multiple studies reference VHA in the context of monoclonal antibody therapies for COVID-19 , but none mention "vha-10."

  • Antibody nomenclature: Standard antibody names (e.g., IgG, IgM, IgA) and therapeutic monoclonals (e.g., tixagevimab/cilgavimab , casirivimab-imdevimab ) follow established conventions. "vha-10" does not align with these patterns.

Analysis of Search Results

Relevant antibody studies in the provided materials focus on:

Antibody TypeKey FindingsSources
Bispecific AntibodiesEngineered for dual antigen targeting; lack Fc-mediated functions in some formats .
Camelid VHH AntibodiesSingle-domain antibodies with small size (~15 kDa) and extended CDR3 loops .
COVID-19 mAbsReduced natural IgM response post-treatment; effective against early infection .
Anti-CD20 AntibodiesLinked to HBV reactivation risks in VHA patients .

None of these studies reference "vha-10" as a distinct antibody.

Potential Explanations for Missing Data

  • Terminology mismatch: The name may refer to an internal project identifier, unpublished research, or a non-standard abbreviation.

  • Typographical error: Possible confusion with terms like VH (variable heavy chain) or VA (variable domain).

  • Therapeutic candidates: No FDA-approved or experimental antibodies named "vha-10" are documented in the provided sources.

Recommendations for Further Research

To resolve ambiguity, consider:

  1. Verify the term with original authors or institutional databases (e.g., VHA research repositories).

  2. Explore alternative nomenclature (e.g., "VH-A10," "VAH-10").

  3. Review patent filings or preclinical studies for proprietary antibody candidates.

Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
vha-10 antibody; F46F11.5 antibody; Probable V-type proton ATPase subunit G antibody; V-ATPase subunit G antibody; Vacuolar proton pump subunit G antibody
Target Names
vha-10
Uniprot No.

Target Background

Function
The vha-10 Antibody targets the catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is a crucial enzyme responsible for acidifying various intracellular compartments within eukaryotic cells.
Database Links
Protein Families
V-ATPase G subunit family

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