ychF Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
ychF antibody; engD antibody; gtp1 antibody; b1203 antibody; JW1194 antibody; Ribosome-binding ATPase YchF antibody
Target Names
ychF
Uniprot No.
Target Background
Function
YchF is an ATPase that exhibits binding affinity for both the 70S ribosome and the 50S ribosomal subunit. This binding is independent of nucleotide presence. Notably, YchF does not hydrolyze GTP.
Gene References Into Functions
- Research findings have shed light on the regulation of the YchF/Ola1 protein family, previously poorly understood. These studies indicate their role as negative regulators in the oxidative stress response. PMID: 26160547
- Further investigation has identified His-114 as a crucial residue for the ATPase activity of YchF in Escherichia coli. PMID: 26018081
- Escherichia coli YchF interacts with the 50S and 70S ribosomal particles in a manner independent of nucleotide presence. Its ATP hydrolysis activity relies on a potassium-dependent mechanism. PMID: 21527254
Database Links
KEGG: ecj:JW1194
STRING: 316385.ECDH10B_1256
Protein Families
TRAFAC class OBG-HflX-like GTPase superfamily, OBG GTPase family, YchF/OLA1 subfamily
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