YMR172C-A Antibody

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Description

Definition and Basic Characterization

YMR172C-A Antibody is a custom-produced polyclonal antibody designed to target the YMR172C-A protein in Saccharomyces cerevisiae (Baker's yeast strain ATCC 204508/S288c). The antibody is cataloged under the product code CSB-PA956640XA01SVG and is associated with the UniProt identifier A0A023PXH6 .

Key Attributes:

PropertyDetails
Target ProteinYMR172C-A
Host SpeciesSaccharomyces cerevisiae (Baker's yeast)
Antibody TypePolyclonal
ApplicationsPresumed for ELISA, Western Blot, Immunofluorescence (not validated)
Available Sizes2 mL or 0.1 mL
Commercial SourceCusabio (Product Page 266)

Biological Context of YMR172C-A

YMR172C-A is a hypothetical protein encoded by the YMR172C-A gene in yeast. While functional studies for this specific protein are absent in public databases, its genomic context suggests it may belong to uncharacterized ORFs (Open Reading Frames) conserved in Saccharomyces species. Such proteins often play roles in:

  • Cellular stress responses

  • Metabolic regulation

  • Genome maintenance .

Research Status and Limitations

No peer-reviewed studies directly investigating YMR172C-A or its corresponding antibody were identified in PubMed, PMC, or specialized antibody databases like YAbS . This absence of data implies:

  • The antibody has not been cited in published experimental workflows.

  • Functional validation (e.g., neutralizing activity, binding affinity) remains unreported.

  • Clinical or industrial applications are undocumented .

Supplier-Reported Data12:

  • Immunogen: Recombinant YMR172C-A protein (exact epitope unspecified).

  • Purification: Affinity-chromatography using protein A/G.

  • Concentration: Not disclosed.

  • Storage: Preserved in PBS (pH 7.4) with 0.02% sodium azide.

Potential Applications (Unverified):

  • Proteomic studies of yeast membrane-associated proteins.

  • Functional genomics to characterize hypothetical yeast ORFs.

Comparative Analysis with Other Yeast Antibodies

The YMR172C-A Antibody belongs to a broader catalog of Saccharomyces cerevisiae-targeting antibodies. For example:

Antibody TargetUniProt IDApplications (Validated)
YME1P32795Mitochondrial protein degradation
YLR402WQ06057Ribosomal biogenesis
YMR172C-AA0A023PXH6Hypothetical protein analysis

Challenges and Future Directions

  • Validation Gap: Independent studies are required to confirm specificity and utility in experimental models.

  • Functional Insights: CRISPR knockout strains or co-immunoprecipitation assays could elucidate YMR172C-A’s role.

  • Therapeutic Potential: No evidence links YMR172C-A to human disease pathways, unlike antibodies targeting viral proteins (e.g., SARS-CoV-2 or influenza ).

Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
YMR172C-A antibody; Putative uncharacterized membrane protein YMR172C-A antibody
Target Names
YMR172C-A
Uniprot No.

Target Background

Subcellular Location
Membrane; Multi-pass membrane protein.

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