PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. Store at -20°C. Avoid freeze-thaw cycles.
Lead Time
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Synonyms
HZF1 antibody; KIAA2007 antibody; Zinc finger protein 1 antibody; Zinc finger protein 266 antibody; Zinc finger protein HZF1 antibody; ZN266_HUMAN antibody; ZNF 266 antibody; ZNF266 antibody
ZNF266 is a zinc finger protein that may be involved in transcriptional regulation.
Gene References Into Functions
HZF1, also known as ZNF266, plays a role in cell cycle regulation. It may function by enhancing CDK2 activity through interaction with and inhibition of INCA1. PMID: 21874239
MEF2 positively regulates the expression of HZF1. PMID: 21468593
Research has identified the trans-activation domain at amino acid residues 49-197 within the non-zinc finger region of HZF1. Three nuclear localization signals have been identified within the zinc finger region. PMID: 19763908
Antisense methods and RNA interference assays have revealed that repression of the intrinsic expression of HZF1 blocks hemin-induced erythroid differentiation and reduces the PMA-induced megakaryocytic differentiation of K562 cells. PMID: 16628192