AMBP Human

Microglobulin Alpha-1 Protein Human

Alpha 1-microglobulin (A1M) is an immunomodulatory protein with a wide range of potential clinical uses. It shows promise as a marker for assessing tubular function.
Shipped with Ice Packs
Cat. No.
BT532
Source
Purified from the urine of patients with chronic renal tubular proteinuria.
Appearance
Sterile Filtered Off-White lyophilized (freeze-dried) powder.

Angiostatin K1-4

Angiostatin Kringles 1-4 Human

Human Angiostatin kringles 1-4, derived from Human Fluid, is a glycosylated polypeptide chain that presents as a doublet with a molecular weight of 50 kDa on SDS-PAGE. The purification of Ang K1-4 is achieved through proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT620
Source
Human Fluid.
Appearance
Sterile Filtered white powder.

CA19-9 Human

CA19-9 Cancer Antigen Human

Human CA19-9 Cancer Antigen, with an approximate molecular weight of 210kDa, was extracted and purified from a human carcinoma cell line.
Shipped with Ice Packs
Cat. No.
BT677
Source

Human carcinoma cell line.

Appearance
The solution is clear and colorless.

GFP

Glial Filament Protein

Highly pure Glial Filament Protein with a molecular weight of 52 kilodaltons (kDa).
Shipped with Ice Packs
Cat. No.
BT1934
Source
Bovine Spinal Cord.
Appearance
Sterile filtered, white, lyophilized (freeze-dried) powder.

Heparin Sodium Porcine

Heparin Sodium Porcine

Heparin Sodium Porcine is a naturally occurring protein derived from pigs.
Shipped with Ice Packs
Cat. No.
BT2027
Source

Porcine Mucosa.

Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.

IgG Human

Immunoglobulin-G Human

Human IgG protein, with a molecular weight of 150kDa, produced in human plasma.
Shipped with Ice Packs
Cat. No.
BT2065
Source

Human serum.

Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.

KRT18 Bovine

Cytokeratin-18 Bovine

KRT18 Bovine is a protein with a calculated molecular mass of 45 kDa and an isoelectric point (pI) of 5.4.
Shipped with Ice Packs
Cat. No.
BT2147
Source

Bovine liver.

Appearance
Sterile Filtered White lyophilized powder.

UTI Human

Urinary Trypsin Inhibitor-Ulinastatin Human

Human Urinary Trypsin Inhibitor is sourced from human urine.

Shipped with Ice Packs
Cat. No.
BT3234
Source
Human Urine.
Appearance

It appears as a sterile white powder that has undergone lyophilization (freeze-drying).

Cyclosporin A

Cyclosporin-A

Cyclosporin, a cyclic polypeptide immunosuppressant composed of 11 amino acids, possesses a molecular weight of 1202.64 g/mol. It is derived as a metabolite from the fungus Beauveria nlyea. The chemical structure of cyclosporin is represented as [R-[R*,R*-(E)]]-cyclic(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-α-amino-butyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl). Its molecular formula is C62H111N11O12.
Shipped with Ice Packs
Cat. No.
BT1103
Source

Beauveria Nivea.

Appearance
White, sterile-filtered powder obtained through lyophilization.

Cytochrome-C Bovine

Cytochrome-C Bovine

Cytochrome-C Bovine is a naturally occurring protein found in bovine tissues.
Shipped with Ice Packs
Cat. No.
BT1180
Source

Bovine.

Appearance
Reddish or dark brown crystalline powder.
Definition and Classification

Natural proteins are large, complex molecules made up of amino acids that play many critical roles in the body. They are classified based on their structure, function, and origin. Other natural proteins refer to those that do not fall into the common categories like enzymes, antibodies, or structural proteins. These can include transport proteins, storage proteins, and regulatory proteins.

Biological Properties

Key Biological Properties: Natural proteins exhibit a wide range of biological properties, including solubility, stability, and specificity. They can be hydrophilic or hydrophobic, and their stability can vary depending on environmental conditions.

Expression Patterns: The expression of natural proteins is tightly regulated and can vary significantly between different tissues and developmental stages. Some proteins are constitutively expressed, while others are induced in response to specific stimuli.

Tissue Distribution: Natural proteins are distributed throughout the body, with specific proteins being localized to particular tissues. For example, hemoglobin is primarily found in red blood cells, while myoglobin is found in muscle tissue.

Biological Functions

Primary Biological Functions: Natural proteins perform a variety of functions, including catalyzing biochemical reactions, transporting molecules, and providing structural support. They also play roles in cell signaling, immune responses, and the regulation of gene expression.

Role in Immune Responses: Some natural proteins, such as cytokines and chemokines, are involved in the immune response by mediating communication between cells and directing the movement of immune cells to sites of infection or injury.

Pathogen Recognition: Proteins like pattern recognition receptors (PRRs) are crucial for recognizing pathogens and initiating an immune response. These proteins can bind to specific molecules found on the surface of pathogens, triggering a cascade of immune reactions.

Modes of Action

Mechanisms with Other Molecules and Cells: Natural proteins interact with other molecules and cells through various mechanisms, including binding to receptors, forming complexes, and undergoing conformational changes. These interactions are often highly specific and are essential for the protein’s function.

Binding Partners: Proteins can have multiple binding partners, including other proteins, nucleic acids, lipids, and small molecules. These interactions can modulate the protein’s activity and function.

Downstream Signaling Cascades: Many natural proteins are involved in signaling pathways that transmit information from the cell surface to the nucleus. These pathways often involve a series of phosphorylation events that activate or inhibit downstream targets, ultimately leading to changes in gene expression.

Regulatory Mechanisms

Regulatory Mechanisms: The expression and activity of natural proteins are regulated at multiple levels, including transcriptional, post-transcriptional, and post-translational.

Transcriptional Regulation: The transcription of protein-coding genes is controlled by various factors, including transcription factors, enhancers, and silencers. These elements can increase or decrease the rate of transcription in response to different signals.

Post-Translational Modifications: After translation, proteins can undergo various modifications, such as phosphorylation, glycosylation, and ubiquitination. These modifications can alter the protein’s activity, stability, and localization.

Applications

Biomedical Research: Natural proteins are widely used in biomedical research to study cellular processes, disease mechanisms, and potential therapeutic targets.

Diagnostic Tools: Proteins can serve as biomarkers for the diagnosis of diseases. For example, elevated levels of certain proteins in the blood can indicate the presence of a specific disease.

Therapeutic Strategies: Natural proteins are used in various therapeutic strategies, including protein replacement therapy, monoclonal antibody therapy, and the development of protein-based drugs.

Role in the Life Cycle

Role Throughout the Life Cycle: Natural proteins play crucial roles throughout the life cycle, from development to aging and disease. During development, proteins are involved in cell differentiation, tissue formation, and organ development. In adulthood, they maintain homeostasis and support various physiological functions. In aging and disease, changes in protein expression and function can contribute to the development of age-related diseases and other pathological conditions.

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