AOC3 Human

Amine Oxidase Copper Containing 3 Human Recombinant

AOC3 Human, produced in Sf9 Baculovirus cells, is a single, glycosylated polypeptide chain consisting of 746 amino acids (specifically, amino acids 27-763). It has a molecular weight of 82.8 kDa. A 9 amino acid His tag is fused to the C-terminus of AOC3. Purification is carried out using proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT18104
Source
Sf9, Baculovirus cells.
Appearance
Sterile Filtered colorless solution.

CPOX Human

Coproporphyrinogen Oxidase Human Recombinant

Recombinant human CPOX, produced in E. coli bacteria, is a single-chain polypeptide without any sugar modifications. It consists of 367 amino acids (specifically, positions 111 to 454), resulting in a molecular weight of 41.6 kilodaltons. This CPOX protein has a 23 amino acid His-tag attached to its N-terminus and is purified using specialized chromatographic methods.
Shipped with Ice Packs
Cat. No.
BT18177
Source
E.coli.
Appearance
A clear, sterile-filtered solution.

DAAO Human

D-Amino Acid Oxidase Human Recombinant

Recombinant human DAAO, expressed in E. coli, is a purified protein engineered with a 20 amino acid His tag at its N-terminus. This non-glycosylated polypeptide chain consists of 367 amino acids (with the DAAO sequence spanning from residues 1 to 347) and has a molecular weight of 41.6 kDa. Purification is achieved using proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT18245
Source
Escherichia Coli.
Appearance
Clear, colorless solution, sterilized by filtration.

DAAO Human, Active

D-Amino Acid Oxidase Human Recombinant, BioActive

Recombinant human DAAO, expressed in E. coli, is a single, non-glycosylated polypeptide chain. It consists of 367 amino acids (residues 1-347), with a molecular weight of 41.6 kDa. This DAAO protein includes an N-terminal His-tag of 20 amino acids. Purification is achieved using proprietary chromatographic techniques.

Shipped with Ice Packs
Cat. No.
BT18321
Source
Escherichia Coli.
Appearance
Clear, sterile-filtered solution.

DMGO

Dimethylglycine Oxidase Recombinant

Recombinant Dimethylglycine oxidase, derived from Arthrobacter globifomis and expressed in E.Coli, is a single, non-glycosylated polypeptide chain. It consists of 850 amino acids with a molecular weight of 92.1 kDa. The DMGO undergoes purification using proprietary chromatographic techniques and is fused with a His Tag at the N-terminal.
Shipped with Ice Packs
Cat. No.
BT18410
Source
Escherichia Coli.
Appearance
Sterile filtered liquid solution at a concentration of 1 mg/ml.

GPX1 Human

Glutathione Peroxidase 1 Human Recombinant

Recombinant human GPX1, produced in E. coli, is a non-glycosylated polypeptide chain consisting of 223 amino acids (1-203). It has a molecular weight of 24.2kDa, achieved by fusing a 20 amino acid His-tag at the N-terminus and purifying it using proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT18480
Source
Escherichia Coli.
Appearance
A clear, colorless solution that has been sterilized by filtration.

GPX2 Human

Glutathione Peroxidase 2 Human Recombinant

Recombinant human GPX2, produced in E.coli, is a single, non-glycosylated polypeptide chain comprising 210 amino acids (1-190) with a molecular weight of 24.1 kDa. It features a 20 amino acid His-tag fused at the N-terminus and is purified using proprietary chromatographic methods.
Shipped with Ice Packs
Cat. No.
BT18535
Source
Escherichia Coli.
Appearance
Clear, colorless solution that has been sterilized by filtration.

GPX3 Human

Glutathione Peroxidase 3 Human Recombinant

Recombinant human GPX3, produced in E. coli, is a single, non-glycosylated polypeptide chain. It comprises 227 amino acids (21-226), resulting in a molecular weight of 25.7 kDa. The protein includes a 21 amino acid His-tag at the N-terminus and undergoes purification using proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT18592
Source
Escherichia Coli.
Appearance
Clear, colorless solution that has been sterilized by filtration.

GPX7 Human

Glutathione Peroxidase 7 Human Recombinant

Recombinant human GPX7, expressed in E. coli, is a single, non-glycosylated polypeptide chain. It consists of 193 amino acids (residues 20-187), resulting in a molecular weight of 21.8 kDa. The protein includes a 25 amino acid His-tag fused at the N-terminus and is purified using proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT18637
Source
E.coli.
Appearance
Clear, colorless solution, sterile-filtered.

HAO1 Human

Hydroxyacid Oxidase 1 Human Recombinant

Recombinant human HAO1, produced in E. coli, is a non-glycosylated polypeptide chain with 406 amino acids (1-370 a.a.) and a molecular weight of 45kDa. The protein consists of a 36 amino acid His-tag fused to the N-terminus and is purified through proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT18708
Source
Escherichia Coli.
Appearance
A clear, sterile solution.
Definition and Classification

Oxidases are a class of enzymes that catalyze the transfer of electrons from a substrate to an oxygen molecule, producing water or hydrogen peroxide as a byproduct. They are a subset of the larger group of enzymes known as oxidoreductases. Oxidases can be classified based on their substrate specificity and the type of reaction they catalyze. Common types include cytochrome oxidases, monoamine oxidases, and xanthine oxidases.

Biological Properties

Key Biological Properties: Oxidases are crucial for various metabolic processes. They exhibit high substrate specificity and are often involved in redox reactions. Expression Patterns: The expression of oxidases varies widely among different tissues and cell types. For instance, cytochrome oxidase is predominantly found in the mitochondria of eukaryotic cells. Tissue Distribution: Oxidases are distributed across various tissues, with specific types localized in particular organs. For example, monoamine oxidase is primarily found in the nervous system and liver.

Biological Functions

Primary Biological Functions: Oxidases play a vital role in cellular respiration, detoxification, and metabolic pathways. They are involved in the breakdown of neurotransmitters and the metabolism of drugs. Role in Immune Responses: Oxidases, such as NADPH oxidase, are essential in the immune response, generating reactive oxygen species (ROS) to combat pathogens. Pathogen Recognition: Certain oxidases are involved in the recognition and neutralization of pathogens, contributing to the body’s defense mechanisms.

Modes of Action

Mechanisms with Other Molecules and Cells: Oxidases interact with various molecules, including substrates, cofactors, and other enzymes, to facilitate redox reactions. Binding Partners: They often require cofactors such as flavin adenine dinucleotide (FAD) or heme groups to function effectively. Downstream Signaling Cascades: The activity of oxidases can trigger downstream signaling pathways, influencing cellular responses such as apoptosis, proliferation, and differentiation.

Regulatory Mechanisms

Expression and Activity Control: The expression and activity of oxidases are tightly regulated at multiple levels, including transcriptional, post-transcriptional, and post-translational modifications. Transcriptional Regulation: Specific transcription factors bind to promoter regions of oxidase genes, modulating their expression in response to cellular signals. Post-Translational Modifications: Oxidases undergo various post-translational modifications, such as phosphorylation and ubiquitination, which can alter their activity, stability, and localization.

Applications

Biomedical Research: Oxidases are extensively studied in biomedical research for their roles in disease mechanisms and potential therapeutic targets. Diagnostic Tools: Enzyme assays involving oxidases are used in diagnostic tests for conditions like diabetes (glucose oxidase) and liver function (xanthine oxidase). Therapeutic Strategies: Inhibitors of specific oxidases, such as monoamine oxidase inhibitors (MAOIs), are used in the treatment of psychiatric and neurological disorders.

Role in the Life Cycle

Development to Aging and Disease: Oxidases are involved in various stages of the life cycle, from development to aging. They play roles in cellular differentiation, growth, and apoptosis. Dysregulation of oxidase activity is associated with aging and diseases such as neurodegenerative disorders, cardiovascular diseases, and cancer.

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