Sprouty Homolog 4 Human Recombinant
Leucine Zipper, Down-Regulated in Cancer 1-Like Human Recombinant
Sequestosome 1 Human Recombinant
Lectin Galactoside-Binding-Like Human Recombinant
Steroid Receptor RNA Activator 1 Human Recombinant
LIM Domain Containing 2 Human Recombinant
Sorcin Human Recombinant
LIN28B Human Recombinant
Serine/arginine-Rich Splicing Factor 1 Human Recombinant
Inducible T Cell Costimulator 4 Human Recombinant
Produced using Sf9 insect cells and baculovirus expression system, the recombinant ICOS protein is a single, glycosylated polypeptide chain. It consists of 362 amino acids with a sequence spanning from amino acid 21 to 140a.a. This protein has a molecular weight of 40.8 kDa. However, it appears as a band of approximately 40-57 kDa on SDS-PAGE due to glycosylation. The ICOS protein is engineered with a 242 amino acid His tag at its C-terminus to facilitate purification. After expression, the protein undergoes rigorous purification using proprietary chromatographic methods to ensure high purity.
The term “Other” can be defined in various contexts. In a general sense, it refers to something or someone that is different or distinct from the one already mentioned or known . In biological taxonomy, classification involves organizing living organisms into hierarchical categories based on their characteristics and evolutionary history .
Biological properties of “Other” can be understood through key characteristics shared by living organisms, such as order, sensitivity or response to stimuli, reproduction, growth and development, regulation, homeostasis, and energy processing . These properties are expressed in various patterns and distributed across different tissues, contributing to the organism’s overall function and survival.
The primary biological functions of “Other” include catalyzing chemical reactions, synthesizing and repairing DNA, transporting materials across cells, receiving and sending chemical signals, responding to stimuli, and providing structural support . These functions play crucial roles in immune responses and pathogen recognition, ensuring the organism’s defense mechanisms are active and effective .
Modes of action describe the functional or anatomical changes resulting from exposure to a substance. This includes the interaction with other molecules and cells, binding partners, and downstream signaling cascades . For example, a mode of action could involve binding to DNA, leading to transcriptional regulation .
Regulatory mechanisms control the expression and activity of “Other” through transcriptional regulation and post-translational modifications . These mechanisms ensure that the biological processes are carried out efficiently and accurately, adapting to the organism’s needs and environmental changes.
In biomedical research, “Other” has various applications, including diagnostic tools and therapeutic strategies . For instance, understanding the biological properties and functions of different molecules can lead to the development of new treatments and diagnostic methods, improving healthcare outcomes.