Protein-L Cys Recombinant, His Tag
Protein L Recombinant, His Tag
Staphylococcal Protein-A 33.4kDa Recombinant
Staphylococcal Protein-A Long Form Recombinant
Produced in E. coli, SPA Recombinant Long Form is a single, non-glycosylated polypeptide chain. This form encompasses five IgG-binding domains (E-D-A-B-C) arranged sequentially, resulting in a protein composed of 422 amino acids with a molecular weight of 46.6kDa.
Staphylococcal Protein-A Recombinant, His Tag
Protein A/G/L Recombinant
Protein A/G/L-Cys Recombinant
Protein G His Tag Recombinant
Protein A/G Recombinant
Recombinant Protein A/G is engineered to optimize IgG binding. It comprises five IgG-binding regions derived from protein A and two from protein G, representing the core binding domains of these proteins. This recombinant version excludes the cell wall binding region, cell membrane binding region, and albumin binding region, ensuring highly specific IgG binding. Specifically, the Protein A portion originates from Staphylococcus aureus segments E, D, A, B, and C, while the Protein G portion comes from Streptococcus segments C1 and C3. With a predicted molecular mass of 47.7kDa, this 429-amino acid fusion protein is a powerful tool for IgG purification and detection.
Protein Cys-A/G Recombinant
Protein A is a 42 kDa surface protein originally found in the cell wall of the bacteria Staphylococcus aureus. It is encoded by the spa gene and is known for its ability to bind immunoglobulins, particularly the Fc region of IgG .
Protein G is derived from Streptococcus species and also binds to the Fc region of IgG. It has a broader binding range compared to Protein A, making it useful for different species and subclasses of IgG .
Protein A/G is a recombinant fusion protein that combines the IgG-binding domains of both Protein A and Protein G. This fusion enhances its binding capabilities, making it ideal for a wide range of IgG subclasses from various species .
Key Biological Properties:
Expression Patterns and Tissue Distribution:
Primary Biological Functions:
Role in Immune Responses and Pathogen Recognition:
Mechanisms with Other Molecules and Cells:
Binding Partners and Downstream Signaling Cascades:
Regulatory Mechanisms Controlling Expression and Activity:
Transcriptional Regulation and Post-Translational Modifications:
In Biomedical Research:
Diagnostic Tools:
Therapeutic Strategies:
Role Throughout the Life Cycle:
From Development to Aging and Disease: