Recombinant Proteins

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Product List

HSA Fatty Acid free

Human Serum Albumin Recombinant, Fatty Acid Free

HSA Human Recombinant Fatty Acid reduced produced in Plant contains 585 amino acids having a molecular mass of 67 kDa.
The recombinant Albumin is purified by proprietary chromatographic techniques.  
Shipped with Ice Packs
Cat. No.
BT14995
Source
Rice Grain.
Appearance

Sterile Filtered clear yellowish solution.

HSA Recombinant, HEK

Human Serum Albumin Recombinant, HEK

Recombinant Human Serum Albumin produced in HEK cells is a glycosylated monomer, having a molecular weight range of 60-65kDa due to glycosylation.
The HSA is purified by proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT15075
Source
HEK.
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.

HSA Recombinant, Plant

Human Serum Albumin Recombinant, Plant

HSA Human Recombinant produced in Plant is a non-glycosylated, polypeptide chain containing 585 amino acids and having a molecular mass of 67 kDa. The optimum concentration for recombinant Albumin to be used in cell culture ranges between 0.5gr to 2gr per liter. The recombinant Albumin is purified by proprietary chromatographic techniques. 

Shipped with Ice Packs
Cat. No.
BT15165
Source
Rice Grain.
Appearance
Sterile Filtered white lyophilized powder.

HSA, Pichia Pastoris

Human Serum Albumin Recombinant, Pichia

HSA Human Recombinant produced in Pichia Pastoris is a polypeptide chain containing 585 amino acids and having a molecular mass of 67 kDa.
The recombinant Albumin is purified by proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT15231
Source
Pichia Pastoris.
Appearance

Yellowish gel like solution.

HSA, Sf9

Serum Albumin Human, Sf9

HSA produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (19-609 a.a.) and fused to a 6 aa His Tag at C-terminus containing a total of 597 amino acids and having a molecular mass of 68kDa.
HSA shows multiple bands between 50-70kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT15300
Source
Sf9, Baculovirus cells.
Appearance
Sterile filtered colorless solution.

Prealbumin Human

Transthyretin Human

Human Transthyretin dimer protein produced in Human plasma having a molecular mass of 30kD. Under certain conditions it may be shown as a monomer (15kD) or a tetramer (60kD).

Shipped with Ice Packs
Cat. No.
BT15399
Source

Human serum.

Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Transthyretin Human

Prealbumin Human Recombinant

Transthyertin Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 128 amino acids (21-147 a.a.) and having a molecular weight of 13.8kDa. The Transthyertin is purified by proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT15479
Source
Escherichia Coli.
Appearance
Sterile filtered colorless solution.

Introduction

Definition and Classification

Albumin is a family of globular proteins, the most common of which are the serum albumins. These proteins are water-soluble, moderately soluble in concentrated salt solutions, and experience heat denaturation . Albumins are commonly found in blood plasma and differ from other blood proteins in that they are not glycosylated . Human serum albumin is the main protein of human blood plasma, making up around 50% of human plasma proteins .

Biological Properties

Key Biological Properties: Albumin is synthesized by hepatocytes in the liver and released into the bloodstream. It has a relatively long half-life, allowing it to perform its functions continuously . Albumin binds to water, cations (such as Ca2+, Na+, and K+), fatty acids, hormones, bilirubin, thyroxine (T4), and pharmaceuticals .

Expression Patterns and Tissue Distribution: Albumin is primarily synthesized in the liver and is found abundantly in blood plasma. It is also present in other body fluids and tissues .

Biological Functions

Primary Biological Functions: Albumin plays a crucial role in maintaining the osmotic balance between blood vessels and surrounding tissues, regulating the distribution of water, electrolytes, and other solutes . It also serves as a carrier protein, transporting various substances in the bloodstream .

Role in Immune Responses and Pathogen Recognition: Albumin exhibits antioxidant properties, scavenging free radicals and protecting against oxidative stress. It also plays a role in the immune response by binding and transporting various substances involved in the immune system .

Modes of Action

Mechanisms with Other Molecules and Cells: Albumin binds to a wide variety of molecules, including hormones, fatty acids, and drugs, facilitating their transport and delivery to different tissues and organs . It also acts as a blood plasma buffer, maintaining acid-base balance .

Binding Partners and Downstream Signaling Cascades: Albumin interacts with various binding partners, including calcium, thyroxine, cortisol, and testosterone . These interactions help regulate the availability and activity of these molecules in the body .

Regulatory Mechanisms

Control of Expression and Activity: The synthesis of albumin is regulated by hormonal factors such as insulin, cortisol, and growth hormone (GH), while pro-inflammatory mediators like interleukin (IL)-6 and tumor necrosis factor (TNF)-α inhibit its production .

Transcriptional Regulation and Post-Translational Modifications: Albumin is synthesized in the liver and undergoes various post-translational modifications that affect its function and stability .

Applications

Biomedical Research: Albumin is widely used in biomedical research due to its ability to bind and transport various substances. It is used as a standard in protein quantification assays and as a stabilizer in biochemical reactions .

Diagnostic Tools: Albumin levels in the blood are used as a diagnostic marker for liver and kidney function, nutritional status, and overall health .

Therapeutic Strategies: Albumin is used therapeutically to treat conditions such as hypoalbuminemia, hypovolemia, and ascites. It is also used in drug delivery systems to enhance the stability and bioavailability of therapeutic agents .

Role in the Life Cycle

Development to Aging and Disease: Albumin plays a vital role throughout the life cycle, from development to aging. It helps maintain fluid balance, transport essential molecules, and protect against oxidative stress. Changes in albumin levels can indicate various health conditions, including liver and kidney disease, malnutrition, and inflammation .

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