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Recombinant Proteins
Product List
RPL26L1 Human
Ribosomal Protein L26-Like 1 Human Recombinant
Recombinant human RPL26L1, expressed in E. coli, is a single polypeptide chain with a molecular weight of 19.6 kDa. It consists of 168 amino acids, including a 23 amino acid His-tag fused at the N-terminus (1-145). The protein is purified using proprietary chromatographic techniques.
Shipped with Ice Packs 
Cat. No.
BT16152
Source
E.coli.
Appearance
Clear, colorless solution, sterile-filtered.
RPS13 Human
Ribosomal Protein S13 Human Recombinant
Recombinant human RPS13, produced in E. coli, is a single, non-glycosylated polypeptide chain. It consists of 174 amino acids (residues 1-151) and has a molecular weight of 19.6 kDa. The protein includes a 23 amino acid His-tag fused to its N-terminus and is purified using proprietary chromatographic techniques.
Shipped with Ice Packs
RPS14 Human
Ribosomal Protein S14 Human Recombinant
RPS14 Human Recombinant is produced in E.Coli. It is fused with a 23 amino acid His tag at its N-terminus. This results in a single, non-glycosylated polypeptide chain containing 174 amino acids (1-151 a.a.) and having a molecular mass of 18.7kDa. The RPS14 protein is purified using proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT17325
Source
Escherichia Coli.
Appearance
Sterile Filtered colorless solution.
RPS3A Human
Ribosomal Protein S3A Human Recombinant
Recombinantly produced in E. coli, the human RPS3A protein is a single polypeptide chain. It consists of 288 amino acids, with a sequence spanning from positions 1 to 264, and exhibits a molecular weight of 32.5 kDa. For purification purposes, a 24 amino acid His-tag is fused to the N-terminus of RPS3A. The protein is further purified using proprietary chromatographic methods.
Shipped with Ice Packs
Cat. No.
BT17976
Source
E.coli.
Appearance
The product is a clear, colorless solution that has been sterilized through filtration.
RPS4X Human
Ribosomal Protein 4X Human Recombinant
This product consists of recombinant human RPS4X protein produced in E. coli. It is a single polypeptide chain with a molecular weight of 32 kDa, comprising 286 amino acids (residues 1-263). The protein includes an N-terminal 23 amino acid His-tag and is purified using proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT18077
Source
Escherichia Coli.
Appearance
A clear, sterile-filtered solution.
RPS5 Human
Ribosomal Protein S5 Human Recombinant
Recombinant human RPS5, produced in E. coli, is a single, non-glycosylated polypeptide chain of 227 amino acids (1-204 a.a.) with a molecular weight of 25.3 kDa. It includes a 23 amino acid His-tag at the N-terminus and is purified using proprietary chromatographic methods.
Shipped with Ice Packs
Cat. No.
BT18163
Source
Escherichia Coli.
Appearance
Clear, colorless, and sterile-filtered solution.
RPS7 Human
Ribosomal Protein S7 Human Recombinant
Recombinant human RPS7, expressed in E. coli, is a single, non-glycosylated polypeptide chain. It consists of 218 amino acids (residues 1-194) with a molecular weight of 24.7 kDa. The protein includes a 24 amino acid His-tag at the N-terminus and is purified using proprietary chromatographic methods.
Shipped with Ice Packs
Cat. No.
BT18235
Source
E.coli.
Appearance
Clear, colorless solution, sterile-filtered.
RPLP1 Human
Ribosomal Phosphoprotein P1 Human Recombinant
RPLP1 is a full-length cDNA that encodes the human ribosomal P1 phosphoprotein. It has a molecular weight of 12,336 Daltons (pH 4.75) and is fused to a hexa-histidine tag for purification.
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RPLP2 Human
Ribosomal Phosphoprotein P2 Human Recombinant
Recombinant RPLP2 Human, produced in E. coli, is a single, non-glycosylated polypeptide chain consisting of 139 amino acids (with a sequence spanning amino acids 1 to 115) and possessing a molecular weight of 14.2 kDa. A 24 amino acid His-tag is fused to the N-terminus of RPLP2. Purification is achieved using proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT17013
Source
Escherichia Coli.
Appearance
A clear, colorless solution that has been sterilized by filtration.
RPS10 Human
Ribosomal Protein S10 Human Recombinant
Recombinant Human RPS10 is produced in E. coli. This single, non-glycosylated polypeptide chain contains 188 amino acids (residues 1-165) with a molecular weight of 21kDa. The protein is purified using proprietary chromatographic techniques and includes an N-terminal His-tag of 23 amino acids.
Shipped with Ice Packs
Cat. No.
BT17085
Source
E.coli.
Appearance
Clear, colorless, and sterile-filtered solution.
Introduction
Definition and Classification
Ribosomal proteins are essential components of ribosomes, the molecular machines responsible for protein synthesis in all living cells. They work in conjunction with ribosomal RNA (rRNA) to form the two subunits of the ribosome: the small subunit and the large subunit. In prokaryotes, these subunits are referred to as 30S (small) and 50S (large), while in eukaryotes, they are 40S (small) and 60S (large) . Ribosomal proteins are highly conserved across different species, reflecting their fundamental role in cellular biology .
Biological Properties
Ribosomal proteins exhibit several key biological properties:
- Expression Patterns: Ribosomal proteins are ubiquitously expressed in all cell types, given their essential role in protein synthesis .
- Tissue Distribution: They are found in all tissues, with particularly high concentrations in rapidly dividing cells and tissues with high protein synthesis demands, such as the liver and bone marrow .
Biological Functions
The primary function of ribosomal proteins is to facilitate the assembly and function of ribosomes in protein synthesis. They play crucial roles in:
- Immune Responses: Some ribosomal proteins are involved in the immune response by recognizing and binding to pathogen-associated molecular patterns (PAMPs) .
- Pathogen Recognition: Certain ribosomal proteins can directly interact with viral RNA, aiding in the immune response against viral infections .
Modes of Action
Ribosomal proteins interact with various molecules and cells through several mechanisms:
- Binding Partners: They bind to rRNA and other ribosomal proteins to form the ribosome’s structural framework .
- Downstream Signaling Cascades: Ribosomal proteins can influence downstream signaling pathways by interacting with other cellular proteins, thereby affecting processes such as cell growth and apoptosis .
Regulatory Mechanisms
The expression and activity of ribosomal proteins are tightly regulated through:
- Transcriptional Regulation: Ribosomal protein genes are regulated by transcription factors that respond to cellular growth conditions and stress .
- Post-Translational Modifications: Ribosomal proteins undergo various post-translational modifications, such as phosphorylation and ubiquitination, which can affect their function and stability .
Applications
Ribosomal proteins have several applications in biomedical research and clinical practice:
Role in the Life Cycle
Ribosomal proteins play vital roles throughout the life cycle:
