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Recombinant Proteins
Product List
RPS12 Human
Ribosomal Protein S12 Human Recombinant
RPS12 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 155 amino acids (1-132 a.a.) and having a molecular mass of 16.9kDa. RPS12 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Shipped with Ice Packs 
RPS16 Human
Ribosomal Protein S16 Human Recombinant
This product consists of the human RPS16 protein recombinantly produced in E. coli. It is a single, non-glycosylated polypeptide chain with 169 amino acids (residues 1-146) and a molecular weight of 18.8 kDa. For purification and detection purposes, a 23 amino acid His-tag is fused to the N-terminus of the protein. Purification is achieved using proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT17388
Source
Escherichia Coli.
Appearance
The product appears as a clear, sterile-filtered solution.
RPS18 Human
Ribosomal Protein S18 Human Recombinant
RPS18 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 175 amino acids (1-152 a.a) and having a molecular mass of 20.1kDa. RPS18 is fused to a 23 amino acid His-tag at the N-terminus and purified by proprietary chromatographic techniques.
Shipped with Ice Packs
RPS19 Human
Ribosomal Protein S19 Human Recombinant
Recombinant human RPS19, produced in E. coli, is a single polypeptide chain comprising 168 amino acids (residues 1-145) with a molecular weight of 18.4kDa. A 23 amino acid His-tag is fused to the N-terminus of RPS19, and the protein is purified using proprietary chromatographic methods.
Shipped with Ice Packs
Cat. No.
BT17570
Source
Escherichia Coli.
Appearance
The product is a clear solution that has been sterilized by filtration.
RPS2 Human
Ribosomal Protein S2 Human Recombinant
Recombinant human RPS2, produced in E. coli, is a single, non-glycosylated polypeptide chain consisting of 316 amino acids (1-293aa). It has a molecular mass of 33.7kDa. The protein includes a 23 amino acid His-tag at the N-terminus and is purified using proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT17634
Source
Escherichia Coli.
Appearance
A clear, sterile-filtered solution.
RPS20 Human
Ribosomal Protein S20 Human Recombinant
This product is a recombinant human RPS20 protein produced in E. coli bacteria. It is a single chain of 165 amino acids with a molecular weight of 18.4kDa. The protein sequence includes amino acids 1-142 of the natural human RPS20 protein. It also includes a 23 amino acid His-tag attached to the N-terminus to aid in purification. The protein is purified using proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT17718
Source
Escherichia Coli.
Appearance
A clear solution that has been sterilized by filtration.
RPS24 Human
Ribosomal Protein S24 Human Recombinant
Recombinant RPS24, produced in E. coli, is a single, non-glycosylated polypeptide chain composed of 153 amino acids (residues 1-130). With a molecular weight of 17.5 kDa, it features a 23 amino acid His-tag fused at the N-terminus. The protein undergoes purification using proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT17775
Source
Escherichia Coli.
Appearance
A clear solution that has undergone sterile filtration.
RPS3 Human
Ribosomal Protein S3 Human Recombinant
This product consists of a recombinant human RPS3 protein produced in E. coli. It is a single, non-glycosylated polypeptide chain comprising 263 amino acids (residues 1-243) with a molecular weight of 28.8 kDa. The protein includes a 20 amino acid His-tag attached to its N-terminus and is purified using proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT17877
Source
E.coli.
Appearance
Clear, colorless solution that has been sterilized through filtration.
RPL35A Human
Ribosomal Protein L35A Human Recombinant
Recombinant Human RPL35A, expressed in E.coli, is a single, non-glycosylated polypeptide chain consisting of 133 amino acids (residues 1-110) with a molecular weight of 14.9kDa. This protein is produced with a 23 amino acid His-tag fused to the N-terminus and purified using proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT16567
Source
Escherichia Coli.
Appearance
A clear solution that has been sterilized by filtration.
RPL5 Human
Ribosomal Protein L5 Human Recombinant
Recombinant RPL5 protein for human use is produced in E. coli. It consists of a single, non-glycosylated polypeptide chain of 320 amino acids (specifically, amino acids 1 to 297) and has a molecular weight of 36.8 kDa. This protein is engineered with a 23 amino acid His-tag at the N-terminus and is purified using proprietary chromatographic methods.
Shipped with Ice Packs
Cat. No.
BT16631
Source
Escherichia Coli.
Appearance
The product is a clear solution that has been sterilized by filtration.
Introduction
Definition and Classification
Ribosomal proteins are essential components of ribosomes, the molecular machines responsible for protein synthesis in all living cells. They work in conjunction with ribosomal RNA (rRNA) to form the two subunits of the ribosome: the small subunit and the large subunit. In prokaryotes, these subunits are referred to as 30S (small) and 50S (large), while in eukaryotes, they are 40S (small) and 60S (large) . Ribosomal proteins are highly conserved across different species, reflecting their fundamental role in cellular biology .
Biological Properties
Ribosomal proteins exhibit several key biological properties:
- Expression Patterns: Ribosomal proteins are ubiquitously expressed in all cell types, given their essential role in protein synthesis .
- Tissue Distribution: They are found in all tissues, with particularly high concentrations in rapidly dividing cells and tissues with high protein synthesis demands, such as the liver and bone marrow .
Biological Functions
The primary function of ribosomal proteins is to facilitate the assembly and function of ribosomes in protein synthesis. They play crucial roles in:
- Immune Responses: Some ribosomal proteins are involved in the immune response by recognizing and binding to pathogen-associated molecular patterns (PAMPs) .
- Pathogen Recognition: Certain ribosomal proteins can directly interact with viral RNA, aiding in the immune response against viral infections .
Modes of Action
Ribosomal proteins interact with various molecules and cells through several mechanisms:
- Binding Partners: They bind to rRNA and other ribosomal proteins to form the ribosome’s structural framework .
- Downstream Signaling Cascades: Ribosomal proteins can influence downstream signaling pathways by interacting with other cellular proteins, thereby affecting processes such as cell growth and apoptosis .
Regulatory Mechanisms
The expression and activity of ribosomal proteins are tightly regulated through:
- Transcriptional Regulation: Ribosomal protein genes are regulated by transcription factors that respond to cellular growth conditions and stress .
- Post-Translational Modifications: Ribosomal proteins undergo various post-translational modifications, such as phosphorylation and ubiquitination, which can affect their function and stability .
Applications
Ribosomal proteins have several applications in biomedical research and clinical practice:
Role in the Life Cycle
Ribosomal proteins play vital roles throughout the life cycle:
