Recombinant Proteins
Product List
Recombinant African swine fever virus Envelope protein p54 (Ba71V-126)
The recombinant African swine fever virus (ASFV) Ba71V-126 protein is a full-length protein expressed in a cell-free E. coli in vitro system. Cell-free systems utilize whole-cell extracts containing all necessary molecules and enzymes for transcription, translation, and post-translational modification of the recombinant protein. Supplementation with cofactors allows for Ba71V-126 protein synthesis within hours. While efficient for rapid production, this system is not suitable for large-scale manufacturing. Key advantages include the elimination of cell culturing and the capacity to co-express multiple proteins.
Ba71V-126, also known as envelope protein p54, is a crucial ASFV antigenic structural protein. p54 is localized within envelope precursors and mature virions (both intracellular and extracellular). It is essential for viral viability and plays a critical role in early infection stages. Research indicates p54's involvement in recruiting envelope precursors to assembly sites, and its central function in viral replication and the induction of specific antibodies following inoculation in pigs with attenuated virus strains.
